[51] The authors concluded that the synergism occured via enhancing G1 cellular arrest, which was confirmed by less DNA synthesis and improved Rb protein (mediator of G1) actions. Ziziphus mauritiana Lam., Encycl. "sidr") which are mentioned in the Quran , [12] [13] while in Palestine it is rather the species Z. spina-christi that is called sidr . With some bioactive polysaccharides (totalling 5.1-6.76% total weight in these two studies,[25][26] reporting a third (not available online) citing 4.42 to 7.91%;[26] these are 77.1% of dry weight, since the fruits have a high water content[27]) consisting of: Neutral polysaccharide (arabinose, xylose, mannose, glucose and galactose at 0.3:0.2:0.2:1:0.7 ratios)[26] which appears to have anti-oxidant properties, Acidic polysaccharides containing rhamnose, arabinose, xylose, mannose, glucose and galactose in a ratio of either 0.3:9.6:0.1:0.4:1:12.1 or 3:16.8:1.2:0.2:1:12.2[26] that are also anti-oxidant in nature, Acidic polysaccharide with rhamnose, arabinose, xylose, glucose and galactose at 21:24:2:1:20[26], Many compounds are structurally similar to Apigenin, as Swertish is an Apigenin molecule with a methoxy (-OCH3) group at the 7-carbon instead of a hydroxy (-OH) group and a single glucose bound to it; Puerarin is an isomer of Swertish with the glucose bound to the 8 carbon rather than the 6 carbon. [1] The botanical name for this plant is Ziziphus zizyphus, and commonly referred to as either Jujube or Jujuba (with the former being technically correct but as common); other names for the fruit of this plant are Chinese Date, Korean Date, Indian Date, or Red Date. and the Indian jujube (Ziziphus mauritiana Lam. [38], Other possible mechanisms associated with neuroprotection could be antagonism of excitotoxicity. for this page. cv. (syn. [43][40], The traditional method of preparation of Jujubes for the purpose of constipation relief to to boil 50g of Jujube fruits (20 whole fruits of 2–2.5 cm in length) to create a soup or drink, which may be related to extraction of a water soluble polysaccharide noted to have anti-constipative effects, and comprise 77% of the dry weight of jujube fruits. https://examine.com/supplements/ziziphus-jujuba/, © 2011-2021 Examine.com Inc | Privacy | Terms of Service | Disclaimer | About Us | Contact Examine.com. Calicut 67. Examine.com and its Editors do not advocate nutritional supplementation over proper medical advice or treatment and this sentiment will never be expressed through pages hosted under Examine.com. Jujubes are also commonly called red dates, Chinese dates, Korean dates or Indian dates. This group has a controversial taxonomy, with more than 200 species described, including Chinese jujube (Ziziphus jujuba Mill. It may possess anxiety-reducing and sedative properties. 1789. [55], The LD50 of an ethyl acetate fraction of Jujube (concentrated flavanoids) appears to be around 2.5g/kg in female mice. [37] Most of this enhancement was due to increased amounts of tertiary dendrites at both concentrations (354% and 579%, respectively), suggesting dendritic proliferation or an attenuation of dendritic loss associated with aging. It also contains Triterpenoids and Phenolic compounds 10, 11. Here, we assembled the complete chloroplast genomes of four best known Ziziphus species, i.e., Ziziphus jujuba, Ziziphus acidojujuba, Ziziphus mauritiana, and Ziziphus spina-christi, based on the Illumina Paired-end sequencing method. Synonyms: Rhamnus Zizyphus L.; Z. sativa Gaertn. Ziziphus mauritiana is widely cultivated in dry areas throughout the tropics. Some other flavonoids contain good quantity of antioxidant, anti-inflammatory and anti-cancerous characteristics. Aim of the experiment was to determine morphological and sensory differences between selected Ziziphus jujube Mill. [2], In a screening of estrogenicity between medical plants, the fruits of Ziziphus (95% ethanolic extract) failed to show any estrogenic or anti-estrogenic effects at concentrations below 1mg/mL.[49]. [40] When a concentration of 0.5g/L was compared to the active control of phenobarbitol, is was slightly but significantly less effective at suppressing the number and amplitude of neuronal population spikes. [30], According to one systemic review on insomnia, the Traditional Chinese Medicine called Suan Zao Ren (which is Ziziphus Jujuba) appears to be the most commonly used insomniac treatment; conclusions on its efficacy in humans could not be drawn due to a lack of good evidence, however. genotypes. (common jujube). (Lam.) "sidrah", pl. Hydroalcoholic extract was achieved according to Nagappan [12] with some modifications. Keywords: Ziziphus jujuba var. If using any pharmaceuticals or drugs given to you by a doctor or received with a prescription, you must consult with the doctor in question or an equally qualified Health Care Professional prior to using any nutritional supplementation. This page is regularly updated, to include the most recently available clinical trial evidence. [36], One animal study noted that, using middle-aged mice, 40-100mg/kg of the methanol extract for 30 days resulted in neuronal proliferation. Ziziphus first appeared in Chinese medical texts in around 300 CE. Basionym: ** Type: MAURITIUS: Without data, Sonnerat s.n. 1982; Ansari, Fl. [38] This was thought to be secondary to anti-oxidant effects in the brain. [41], Jujuboside A has been demonstrated to reduce excitatory postsynaptic potential in hippocampal neurons,[42] and has been shown to reduce EEG readings in rats given intracerebral injections of Jujuboside A. [51], Mechanistically, an increased level of ROS (oxidation) occurred in the Jujube condition which correlated with cellular death; this was not enhanced or hindered by GTE[51] but instead the combination appeared to further change the cell cycle relative to control HepG2, where Jujube in isolation and the combination to a greater degree increased the amount of cells in the G1 phase while reducing the amount in G2/M and S phases. var. In terms of energetic properties, it was thought to be the perfect balance of warming and cooling. [27] These authors hypothesized that the increase in SCFAs explained the observed effects, as SCFAs have been previously linked to mucosal stimulation[44] although the decrease in mucosinase may also partly explain the moisture content. Jujuboside A appears to have anti-calmodulin activities in preventing calcium influx into glutaminergic neurons (although the concentration used in this study may not be applicable to oral Jujube ingestion; too high)[39] although similar effects have been noted at lower concentrations. The ratio between herbs and the mixture was 2: 8. Ziziphus Jujuba (Chinese/Korean Date, Jujube) is a plant which bears fruits and seeds that are used for medicinal purposes in Traditional Chinese Medicine. Ziziphusis a genus of spiny shrubs and small trees in the Rhamnaceae family. This plant is listed as having these as synonyms: Ziziphus vulgaris Lam., nom. (holotype: P). Examine.com is intended to be used for educational and information purposes only. There are two major domesticated jujubes, Ziziphus mauritiana Lam. County Herbaria Literature Citation (If Applicable) Broward: USF Glades: FLAS : Miami-Dade: USF + Expand All - Collapse Synonyms – Denotes synonyms that are applicable to the state. Examine.com does not assume liability for any actions undertaken after visiting these pages, and does not assume liability if one misuses supplements. [28], 200µg/mL of ziziphus jujuba (fruit) has failed to significantly inhibit acetylcholinesterase in vitro, inhibiting merely 2.4+/-2.6% of activity. This plant is known as Ennab and Annab in the Arabic and Persian languages, respectively. Jujube has a long history of usage as a fruit and remedy. Jujube flavonoids have once been found to act synergistically with 2mg/kg 5-HTP in inducing sleep in rats. [52], 5-HTP is an animo acid derivative that is made from tryptophan, and proceeds to be metabolized into the neurotransmitter serotonin and subsequently melatonin; secondary to melatonin, it may help sleep. Ziziphus lotus L. [46] Serum Nitrate showed similar results, with a dose-dependent reduction with Jujube but more efficacy with Indomethacin. [29], The seeds of Ziziphus jujube have been implicated in reducing anxiety, in accordance with their traditional usage. The main biologically active components are vitamin C, phenolics, flavonoids, triterpenic acids, and polysaccharides. Briefly, 20 grams of powder were macerated with 88% ethanol (5 volumetric parts) and water (5 volumetric parts). spinosa, Ziziphus mauritiana, saponins, flavonoids, fatty acids, chemometrics. [37], In response to Ischemia, oral ingestion of a methanolic extract of Ziziphus (dose undisclosed) appears to protect neurons from cell death (with Ischemia having 11.3% of control and ingestion of Ziziphus attenuating this to 58.4% as assessed by neuronal nuclei immunoreactivity four days after Ischemia) and was about as effective as the active control of 100mg/kg Ebselen. Of Iran the correct scientific name use cookies to help provide and enhance our service and tailor and! 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